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melasma is commonly known as a chronic
hyperpigmentation skin disease that affects up to 50 per cent of the population, of all skin colours, worldwide. there is also a genetic predisposition — up to half of patients with melasma also have a family member with the condition. the prevalence of melasma is the highest among females, and darker skin types including indian, latino, asian, hispanic, middle eastern and african descents.
and while this skin condition is benign, it can have a profound negative affect on quality of life and self-esteem because of its perceived effect on attractiveness.
psychosocial and emotional distress
patients with melasma often describe feeling shame, frustration, low self-esteem, a lack of motivation to go out, and experience a higher degree of expenditures on treatments and cosmetics to combat the appearance of their skin. interestingly, quality of life scores do not necessarily correlate to the severity of pigmentation changes, suggesting that any degree of pigment can be impactful to the individual.
what causes melasma?
repeated ultraviolet radiation (uv) exposure is a cause of melasma. basically, sunlight stimulates the skin to produce more melanin in some areas than others — thus, the uneven patches of colour that defines this condition.
of course, we already know that sun damages the skin, flattening the layers of skin and accelerating collagen and elastin breakdown. these biological processes and physical changes beneath the skin allow pigment to move deeper and can decrease the effectiveness of treatments.
melasma also seems to be related to female hormones, and tends to occur most commonly during pregnancy or in women who use oral contraceptives. but there are other important contributing factors, including other hormones (thyroid, adrenal, pituitary, msh), as well as topical cosmetic use, medications that increase sun sensitivity, and heat exposure — all of which affect the production of skin pigment.